A pilot study of the utility of cerebrospinal fluid neurofilament light chain in differentiating neurodegenerative from psychiatric disorders: A 'C-reactive protein' for psychiatrists and neurologists?
Dhamidhu EratneSamantha M Loi Franzcp PhD MbbsNirbaanjot WaliaSarah FarrandQiao-Xin LiShiji VargheseMark WalterfangAndrew EvansRamon MocellinKunal DhimanVeer GuptaCharles B MalpasSteven CollinsColin L MastersDennis VelakoulisPublished in: The Australian and New Zealand journal of psychiatry (2019)
Cerebrospinal fluid neurofilament light shows promise as a diagnostic test to assist with the often challenging diagnostic dilemma of distinguishing psychiatric disorders from neurodegenerative and neurological disorders. Further studies are warranted to replicate and expand on these findings, including on plasma neurofilament light.