Serum biomarkers can predict a change in liver fibrosis 1 year after lifestyle intervention for biopsy-proven NASH.

Eduardo Vilar-GomezLuis Calzadilla-BertotScott L FriedmanBienvenido Gra-OramasLicet Gonzalez-FabianSacha Lazo-Del VallinMoises DiagoLeon A Adams

Published in: Liver international : official journal of the International Association for the Study of the Liver (2017)

Change in NFS, platelets and ALT normalization are associated with change in liver fibrosis after 1 year of LI. A model including change in HbA1c, platelet and ALT normalization discriminated patients with fibrosis improvement significantly better than other biomarkers.

Keyphrases

liver fibrosis
cardiovascular disease
metabolic syndrome
physical activity
type diabetes