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Elevated Levels of SOX10 in Serum from Vitiligo and Melanoma Patients, Analyzed by Proximity Ligation Assay.

Andries BlokzijlLei E ChenSigrun M GustafsdottirJimmy VuuGustav UllenhagOlle KämpeUlf LandegrenMasood Kamali-MoghaddamHåkan Hedstrand
Published in: PloS one (2016)
We show for the first time that SOX10 represents a promising new serum melanoma marker for detection of early stage disease, complementing the established S100B marker. Our findings imply that SOX10 can be used to monitor responses to treatment and to assess if the treatment is of benefit at stages earlier than what is possible radiologically.
Keyphrases
  • early stage
  • stem cells
  • transcription factor
  • ejection fraction
  • newly diagnosed
  • squamous cell carcinoma
  • radiation therapy
  • combination therapy
  • lymph node
  • replacement therapy