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VeloPro: A pipeline integrating Ribo-seq and AlphaFold deciphers association patterns between translation velocity and protein structure features.

Bian BianToshitaka KumagaiYutaka Saito
Published in: iMeta (2023)
VeloPro integrates Ribo-seq data and AlphaFold2-predicted 3D protein structure information for characterization of the association patterns between translation velocity and many protein structure features in prokaryotic and eukaryotic organisms across different taxonomical clades such as bacteria, fungi, protozoa, nematode, plants, insect, and mammals. We illustrated that association patterns between translation velocity and protein structure features differ across organisms, partially reflecting their taxonomical relationship.
Keyphrases
  • protein protein
  • binding protein
  • amino acid
  • blood flow
  • single cell
  • genome wide
  • gene expression
  • dna methylation
  • machine learning
  • gram negative
  • electronic health record
  • multidrug resistant
  • data analysis