Genome-wide 5-hydroxymethylcytosines in circulating cell-free DNA as noninvasive diagnostic markers for gastric cancer.

Yingli FuJing JiangYanhua WuDonghui CaoZhifang JiaYangyu ZhangDongming LiYingnan CuiYuzheng ZhangXueyuan Cao

Published in: Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association (2024)

The characteristics of 5-hydroxymethylcytosine in cell free DNA are specific to gastric cancer patients, and the diagnostic model constructed by five genes' 5-hydroxymethylcytosine features could effectively identify gastric cancer patients.

Keyphrases

genome wide
dna methylation
copy number
gene expression
bioinformatics analysis