Genotyping analysis of MNS blood group GP(B-A-B) hybrid glycophorins in the Chinese Southern Han population using a high-resolution melting assay.

Ling WeiGenghis H LopezYang ZhangJizhi WenZhen WangYongshui FuCatherine A Hyland Robert L P FlowerGuangping LuoYanli Ji

Published in: Transfusion (2018)

The HRM assay could distinguish the GYP(B-A-B) hybrid alleles successfully. Polymorphisms identified within the GYPB gene should be taken into consideration when developing GYP(B-A-B) genotyping kits for the Chinese population.

Keyphrases

high throughput
high resolution
genome wide
single cell
copy number
dna methylation
mass spectrometry
genetic diversity
high speed
tandem mass spectrometry
genome wide identification
gene expression
genome wide analysis