Protective Effects of Oenothera biennis against Hydrogen Peroxide-Induced Oxidative Stress and Cell Death in Skin Keratinocytes.

Seung Young LeeChul Hwan KimBuyng Su HwangKyung-Min ChoiIn-Jun Yang Gi Young Kim Young Hyun ChoiCheol ParkJin-Woo Jeong

Published in: Life (Basel, Switzerland) (2020)

APOB can protect HaCaT cells from H2O2-induced DNA damage and cell death by blocking cellular damage related to oxidative stress via a mechanism that affects ROS elimination and by activating the Nrf2/HO-1 signaling pathway.

Keyphrases

hydrogen peroxide
cell death
oxidative stress
diabetic rats
dna damage
signaling pathway
pi k akt
induced apoptosis
nitric oxide
cell cycle arrest
ischemia reperfusion injury
wound healing
dna repair
high glucose
epithelial mesenchymal transition
drug induced
heat shock