Adjuvant hysterectomy following primary chemoradiation for stage IB2 and IIA2 cervical cancer: a retrospective comparison of complications for open versus minimally invasive surgery.
Heather MillerKoji MatsuoLynda D RomanAnnie A YessaianHuyen Q PhamMarianne HomAntonio CastanedaAnthony PhamOmar RagabLaila MuderspachMarcia CicconeLaurie L BrunettePublished in: Radiation oncology (London, England) (2021)
Among women undergoing adjuvant hysterectomy following chemoradiation for bulky, early stage cervical cancer, there was no difference in complication rates between an open or minimally invasive surgical approach. However, the overall complication rate was high, including a high rate of vaginal cuff defect, dehiscence and/or fistulas. Our findings suggest that an adjuvant hysterectomy should be reserved for patients in which chemoradiation is not anticipated to successfully treat the primary tumor and, if performed, an open approach should be considered.
Keyphrases
- early stage
- minimally invasive
- rectal cancer
- locally advanced
- end stage renal disease
- ejection fraction
- newly diagnosed
- sentinel lymph node
- chronic kidney disease
- peritoneal dialysis
- polycystic ovary syndrome
- prognostic factors
- radiation therapy
- type diabetes
- neoadjuvant chemotherapy
- metabolic syndrome
- skeletal muscle
- pregnancy outcomes
- insulin resistance
- robot assisted
- cervical cancer screening
- soft tissue