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Clinical Characteristics and Treatment of Listeria monocytogenes Infections in the Central Nervous System.

Xiaojiao XuYuheng ShanYuying CenJiahua ZhaoXiaosa YangRui LiuQingche TanYubao MaMianwang HeJiatang ZhangFei YangSheng-Yuan Yu
Published in: Infection and drug resistance (2023)
Monitoring the proportion of monocytes in blood and mNGS results of CSF can play a crucial role in diagnosing pathogens. Early and sufficient application of two to three sensitive antibiotics with a BBB permeability of 20-30% for at least 2-3 months can significantly improve CNS listeriosis prognosis.
Keyphrases
  • listeria monocytogenes
  • blood brain barrier
  • cerebrospinal fluid
  • endothelial cells
  • dendritic cells
  • gram negative
  • peripheral blood
  • antimicrobial resistance
  • combination therapy
  • smoking cessation