A prospective study on dual time 18F-FDG-PET/CT in high-risk prostate cancer patients.
Mike Allan MortensenMie Holm VilstrupMads Hvid PoulsenOke GerkePoul Flemming Høilund-CarlsenLars LundPublished in: BMC research notes (2018)
Twenty patients with high-risk prostate cancer underwent dual time point FDG-PET/CT before undergoing surgery. Histologically confirmed lymph node metastases were found in 9/20 (45%). A median of 19 (range 10-41; n = 434) lymph nodes were removed per patient. Pelvic lymph nodes with detectable FDG uptake were seen in two patients only, but the FDG-avid lesion on PET did not correspond with pathological findings in either patient. We found a significant increase in maximal standardized uptake value of the prostate of around 30% between early and late imaging. We found no correlation between clinical findings after radical prostatectomy and PET measurements.
Keyphrases
- prostate cancer
- lymph node
- radical prostatectomy
- end stage renal disease
- ejection fraction
- pet ct
- positron emission tomography
- newly diagnosed
- chronic kidney disease
- pet imaging
- computed tomography
- peritoneal dialysis
- prognostic factors
- squamous cell carcinoma
- minimally invasive
- neoadjuvant chemotherapy
- sentinel lymph node
- early stage
- blood pressure
- patient reported outcomes
- atrial fibrillation
- acute coronary syndrome
- percutaneous coronary intervention