Genetically proxied IL-6 signaling and risk of Alzheimer's disease and lobar intracerebral hemorrhage: A drug target Mendelian randomization study.
Evangelos Pavlos MyserlisAnushree RayChristopher D AndersonMarios K GeorgakisPublished in: Alzheimer's & dementia (New York, N. Y.) (2024)
Genetic variants proxying IL-6 inhibition are associated with AD and lobar ICH risk.The variants are also associated with amyloid clearing-related proteomic changes.Whether pharmacologic IL-6 inhibition is linked to AD or lobar ICH merits further study.
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