Multiple cerebral cavernous malformations: Clinical course of confirmed, assumed and non-familial disease.

Alejandro Nicolas Santos Laurèl Rauschenbach Dino Vitali SabanBixia ChenMarvin Darkwah Oppong Annika HertenHanah Hadice GullChristoph RießCornelius DeuschlBörge SchmidtRamazan JabbarliKarsten Henning WredeYuan ZhuBenedikt FrankUlrich SurePhilipp Dammann

Published in: European journal of neurology (2022)

FCCM patients with ICH at diagnosis are prone to develop rebleeding. During untreated 5-year FU, FCCM patients and patients with sporadic multiple CCM reveal an almost equal susceptibility for (re)hemorrhage. Moreover, confirmed, assumed and non-FCCM patients showed an equal cumulative 5-year risk of symptomatic ICH. The probability of hemorrhage tends to increase over time, particularly in cases with ICH at presentation.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
peritoneal dialysis
gene expression
dna methylation
patient reported outcomes
late onset
genome wide
subarachnoid hemorrhage
single cell