Protein Structure Inspired Drug Discovery.

Fangfang QiaoT Andrew BinknowskiIrene BroughanWeining ChenAmarnath NatarajanGary E SchiltzKarl A ScheidtWayne F AndersonRaymond C Bergan

Published in: bioRxiv : the preprint server for biology (2024)

We introduce the concept that protein 3D structure represents primary information which can support downstream investigations, in this instance leading to the discovery of novel anticancer therapeutics.

Keyphrases

drug discovery
small molecule
protein protein
amino acid
binding protein
high throughput
single cell