Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study.

Fabrice UhelHessel Peters-SengersFahimeh FalahiBrendon P SciclunaLonneke A van VughtMarc J BontenOlaf L CremerMarcus J SchultzTom van der Pollnull null

Published in: Intensive care medicine (2020)

Persistent AKI is independently associated with sepsis mortality, as well as with sustained inflammatory and procoagulant responses, and loss of vascular integrity as compared with transient AKI.

Keyphrases

acute kidney injury
cardiovascular events
intensive care unit
septic shock
risk factors
oxidative stress
copy number
cardiovascular disease
gene expression
genome wide