Login / Signup

The transcriptome-wide association search for genes and genetic variants which associate with BMI and gestational weight gain in women with type 1 diabetes.

Agnieszka H Ludwig-SłomczyńskaMichał T SewerynPrzemysław KapustaEwelina PiteraUrszula MantajKatarzyna CyganekPaweł GutajŁucja DobruckaEwa Wender-OżegowskaMaciej T MałeckiPawel P Wolkow
Published in: Molecular medicine (Cambridge, Mass.) (2021)
Here, we have shown that loci influencing BMI might have an impact on GWG and GWG associated loci might influence BMI, both in the general and T1DM cohorts. The results suggest that both phenotypes are related to insulin signaling, glucose homeostasis, mitochondrial metabolism, ubiquitinoylation and inflammatory responses.
Keyphrases