A Method to Amend Cigarettes with Menthol for use in Research.
Kia J JacksonMegan J SchroederJiu AiKenneth M TaylorOlusola OniyideLauren C VirayCarson SmithBartosz KoszowskiJenny M ButlerWallace B PickworthPublished in: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco (2023)
This study presents a technique for modifying cigarettes with different levels of menthol that can reliably deliver dose-related menthol levels to participants when smoked in a clinical study. The technique can be used to quickly amend cigarettes to examine the independent effects of varying flavor and additive levels on smoking behavior, nicotine pharmacokinetics, mainstream smoke emissions, and other laboratory or clinical research outcomes.