Loss of myocardial Hey2/Hrt2 function disrupts rightward shift of atrioventricular cushion tissue and causes tricuspid atresia.

Kazuki OkumuraTomoko IokaMasahide Sakabe

Published in: Developmental dynamics : an official publication of the American Association of Anatomists (2023)

Disruption of rightward cushion movement is an initial cue of TA phenotype, and myocardial HEY2/HRT2 is necessary for the regulation of proper alignment of AV endocardial cushion tissue. This article is protected by copyright. All rights reserved.

Keyphrases

left ventricular
mitral valve
aortic valve
catheter ablation