Effect of Prophylactic Dose of Trimethoprim-Sulfamethoxazole on Serum Creatinine in Japanese Patients With Connective Tissue Diseases.
Rui KawatoRyo RokutandaMasato OkadaMasakazu MatsushitaKen YamajiNaoto TamuraPublished in: Clinical medicine insights. Arthritis and musculoskeletal disorders (2022)
These results demonstrated that baseline SCr and advanced age were associated with SCr elevation by a prophylactic dose of TMP/SMX. However, a prophylactic dose of TMP/SMX rarely elevated the SCr level significantly. Therefore, other causes can be considered if patients show an SCr elevation ⩾0.3 mg/dL.