Dracorhodin targeting CMPK2 attenuates inflammation: A novel approach to sepsis therapy.
Wendan ZhangHonghong JiangPengli HuangGaosong WuQun WangXin LuanHongwei ZhangDianping YuHongru WangDong LuHaonan WangHuazhang AnSan-Hong LiuWeidong ZhangPublished in: Clinical and translational medicine (2023)
We provide a new framework that provides more valuable information for new therapeutic approaches to sepsis, including the establishment of screening strategies and the development of target drugs to provide a theoretical basis for ultimately improving clinical outcomes for sepsis patients. Collectively, these findings reveal that DP is a promising CMPK2 inhibitor for the treatment of sepsis.