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Modelling stripe formation in zebrafish: an agent-based approach.

Alexandria VolkeningBjörn Sandstede
Published in: Journal of the Royal Society, Interface (2016)
Zebrafish have distinctive black stripes and yellow interstripes that form owing to the interaction of different pigment cells. We present a two-population agent-based model for the development and regeneration of these stripes and interstripes informed by recent experimental results. Our model describes stripe pattern formation, laser ablation and mutations. We find that fish growth shortens the necessary scale for long-range interactions and that iridophores, a third type of pigment cell, help align stripes and interstripes.
Keyphrases
  • induced apoptosis
  • stem cells
  • single cell
  • cell therapy
  • cell cycle arrest
  • oxidative stress
  • wound healing