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Correlation between depression scores and serum NF-ĸB/NLRP3 axis, biotinidase, and HMGB1 after treatment with isotretinoin in patients with acne vulgaris.

Ammena Y BinsalehLahin Saad AliMostafa M BahaaThanaa A ElmasryWalaa A NegmAmir O HamoudaMuhammed M SalahuddinEman WahshMarwa Ahmed El-SamongyNawal AlsubaieEman El-KhateebMohamed YasserNashwa Eltantawy
Published in: Journal of cosmetic dermatology (2024)
Increased GAGS, HMGB1, NLRP3, and biotinidase were associated with depression severity in AV patients and ISO treatment significantly reduced these parameters and reduced depressive symptoms.
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