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Impact of performance status and transfusion dependency on outcome of patients with myelodysplastic syndrome, acute myeloid leukemia and chronic myelomonocytic leukemia treated with azacitidine (PIAZA study).

Jürgen WehmeyerMatthias ZaissChristoph LosemStephan SchmitzBeate NiemeierJohanna HardeCarla Verena HannigHanns-Detlev HarichJudith MüllerMartine KlausmannHans Werner TessenKarin Potthoff
Published in: European journal of haematology (2018)
In conclusion, we estimated the duration of PFS in a real-world setting and identified ECOG PS and RBC transfusion as predictive factors for PFS. The safety of azacitidine showed a similar profile as demonstrated in the pivotal clinical trials.
Keyphrases
  • acute myeloid leukemia
  • clinical trial
  • allogeneic hematopoietic stem cell transplantation
  • cardiac surgery
  • sickle cell disease
  • acute kidney injury
  • red blood cell
  • open label
  • phase ii
  • newly diagnosed