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Spermatic mitochondria: role in oxidative homeostasis, sperm function and possible tools for their assessment.

João Diego de Agostini LosanoDaniel de Souza Ramos AngrimaniRoberta Ferreira LeiteBárbara do Carmo Simões da SilvaValquíria Hyppolito BarnabeMarcilio Nichi
Published in: Zygote (Cambridge, England) (2018)
SummaryDespite sperm mitochondrial relevance to the fertilization capacity, the processes involved in the production of ATP and functional dynamics of sperm mitochondria are not fully understood. One of these processes is the paradox involved between function and formation of reactive oxygen species performed by the organelle. Therefore, this review aimed to provide data on the role of sperm mitochondria in oxidative homeostasis and functionality as well the tools to assess sperm mitochondrial function.
Keyphrases
  • reactive oxygen species
  • cell death
  • endoplasmic reticulum
  • oxidative stress
  • big data