Regulatory Variants on the Leukocyte Immunoglobulin-Like Receptor Gene Cluster are Associated with Crohn's Disease and Interact with Regulatory Variants for TAP2.

Kwangwoo KimShin Ju OhJunho LeeAyeong KwonChae-Yeon YuSangsoo KimChang Hwan ChoiSang-Bum KangTae Oh KimDong Il ParkChang Kyun Lee

Published in: Journal of Crohn's & colitis (2023)

This study demonstrated that genetic variants at two novel susceptibility loci and the epistatic interaction between variants in LILR and TAP2 loci confer risk of CD.

Keyphrases

copy number
genome wide
transcription factor
dna methylation
genome wide association study
genome wide association
gene expression
binding protein
genome wide analysis