Protective effects of esculetin against ovary ischemia-reperfusion injury model in rats.

Mehmet GüvençMurat YükselTuncer KutluMuhammed Etyemezİshak GökçekMustafa Cellat

Published in: Journal of biochemical and molecular toxicology (2023)

Our results proved the protective effect of esculetin against ovarian IR injury in rats and this may be attributed to Nrf-2/NF-κβ axis which showed antioxidant and anti-inflammatory effects. Therefore, esculetin can be used in the future for preventive effects to ovarian IR injury.

Keyphrases

oxidative stress
ischemia reperfusion injury
signaling pathway
current status
lps induced
anti inflammatory
nuclear factor
pi k akt
immune response