PARP targeted Auger emitter therapy with [ 125 I]PARPi-01 for triple-negative breast cancer.

Ramya Ambur SankaranarayanaAlexandru FloreaSusanne AllekotteAndreas T J VoggJochen MaurerLaura SchäferCarsten BolmSteven TerhorstArno ClassenMatthias BauwensAgnieszka MorgenrothFelix Manuel Mottaghy

Published in: EJNMMI research (2022)

I]PARPi-01 presents a potential radiotherapeutics for treatment of TNBC. Improvements to overcome the suboptimal pharmacokinetics are necessary for its potential clinical application.

Keyphrases

dna damage
dna repair
cancer therapy
human health
drug delivery
risk assessment
bone marrow
smoking cessation