Distinct disease mechanisms may underlie cognitive decline related to hearing loss in different age groups.
Jochum J van 't HooftWiesje PelkmansJori TomassenCas SmitsNienke LegdeurAnouk den BraberFrederik BarkhofBart van BerckelMaqsood YaqubPhilip ScheltensYolande A L PijnenburgPieter Jelle VisserBetty M TijmsPublished in: Journal of neurology, neurosurgery, and psychiatry (2023)
Hearing loss was associated with amyloid binding in younger-old individuals only, and with cognitive decline in both age groups. These results suggest that mechanisms linking hearing loss with risk for dementia depends on age.