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Peripapillary hyperreflective ovoid mass-like structures (PHOMS): OCTA may reveal new findings.

Enrico BorrelliPiero BarboniMarco BattistaRiccardo SacconiLea QuerquesMaria Lucia CascavillaFrancesco BandelloGiuseppe Querques
Published in: Eye (London, England) (2020)
Assuming that PHOMS are thought to correspond to herniating nerve fibers or be secondary to axoplasmic stasis, this vascular complex may represent a displacement of the deeper vessels deputed at the irroration of the optic nerve into the retina or, alternatively, might be secondary to an increase in vascular endothelial growth factor (VEGF) levels and a subsequent development of neovessels.
Keyphrases
  • optic nerve
  • vascular endothelial growth factor
  • optical coherence tomography
  • endothelial cells
  • high resolution
  • genome wide
  • single cell
  • gene expression
  • mass spectrometry