RIPK3 activation promotes DAXX-dependent neuronal necroptosis after intracerebral hemorrhage in mice.

Qingqing BaiShuoyang WangDongmei RaoZhiming ZhouJianfei WangQi WangYu QinZhaohu ChuShoucai ZhaoDijing YuYang Xu

Published in: CNS neuroscience & therapeutics (2023)

RIPK3 revitalization promoted neuronal necroptosis in ICH mice, partially through the DAXX signaling pathway. RIPK3 and AIF interacted with nuclear DAXX to aggravate ICH injury.

Keyphrases

signaling pathway
high fat diet induced
brain injury
cerebral ischemia
epithelial mesenchymal transition
insulin resistance
wild type
metabolic syndrome
induced apoptosis
cell proliferation
endoplasmic reticulum stress