Prion-related peripheral neuropathy in sporadic Creutzfeldt-Jakob disease.

Simone BaiardiVeronica RedaelliPaolo RipellinoMarcello RossiAlessia FranceschiniMaurizio MoggioPatrizia SolaAnna LadoganaPaolo FocianiAnna MagheriniSabina CapellariArmin GieseByron CaugheyPaola CaroppoPiero Parchi

Published in: Journal of neurology, neurosurgery, and psychiatry (2018)

Peripheral neuropathy, likely related to PrPSc deposition, belongs to the phenotypic spectrum of sCJDMV2K and VV2 and may mark the clinical onset. The significantly lower prevalence of PNS involvement in typical sCJDMM(V)1 suggests that the PNS tropism of sCJD prions is strain dependent.

Keyphrases

risk factors
late onset
early onset
drug induced