Caffeic Acid Phenethyl Ester Improves Metabolic Syndrome by Activating PPAR-γ and Inducing Adipose Tissue Remodeling in Diet-Induced Obese Mice.

Soon-Hee KimHee-Sook ParkMoon Ju HongHaeng Jeon HurDae Young KwonMyung Sunny Kim

Published in: Molecular nutrition & food research (2018)

CAPE ameliorates metabolic disease by inducing PPAR-γ activation and AT remodeling. Additionally, this study reveals that the intake of CAPE after obesity, as well as in the early stage of obesity, helps in the prevention and treatment of MetS.

Keyphrases

insulin resistance
metabolic syndrome
adipose tissue
south africa
early stage
high fat diet induced
high fat diet
skeletal muscle
weight gain
type diabetes
weight loss
uric acid
signaling pathway
cardiovascular risk factors
mouse model
combination therapy
sentinel lymph node
rectal cancer
physical activity