Impact of M-protein detection on the response evaluations of patients undergoing treatment with the IgG-κ monoclonal antibodies daratumumab or isatuximab, and discrepancies between immunofixation electrophoresis (IFE) systems and reagents.
Yuko ShirouchiKazumi KaiharaTsunaki SekitaNaoko AmanoKonosuke NakayamaKazunori MiyakeHitoshi AbeHirotoshi OinumaDai MaruyamaPublished in: Cancer medicine (2024)
Sensitivity and specificity of M-protein detection vary greatly depending on the IFE system and reagents used.