Association of MTHFR C677T polymorphism and type 2 diabetes mellitus (T2DM) susceptibility.

Yanzi MengXiaoling LiuKai MaLili ZhangMao LuMinsu ZhaoMin-Xin GuanGuijun Qin

Published in: Molecular genetics & genomic medicine (2019)

Our results indicated that MTHFR C677T polymorphism confers to T2DM, especially in Asian populations. Much more large-scale case-control studies are needed to strengthen such conclusion in the future.

Keyphrases

case control
glycemic control
type diabetes
current status
genetic diversity
insulin resistance
cardiovascular risk factors