Elucidating the role of transiently hypoxic tumour cells on radiation resistance.
Geoff S HigginsEva-Leonne GöttgensPublished in: British journal of cancer (2022)
The link between hypoxic conditions and radiation sensitivity is well-established, however the dynamic nature of hypoxia is often overlooked. The contribution of acute/transient hypoxia versus chronic conditions to radiosensitivity has been investigated by Wadsworth et al. using two hypoxia markers and pentoxifylline to increase blood flow to regions of transient hypoxia.