De novo design of stable proteins that efficaciously inhibit oncogenic G proteins.
Matthew C CumminsAshutosh TripathyJohn SondekBrian KuhlmanPublished in: bioRxiv : the preprint server for biology (2023)
, which is an oncogene for uveal melanomas. This computational method is a general approach that should be useful for designing competitive inhibitors against other proteins of interest.
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