High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells.

Lixian LiuJunjing JiaMin JiangXueping LiuChenling DaiBarton L WiseNancy E LaneWei Yao

Published in: Arthritis research & therapy (2020)

The presence of PR in osteoprogenitor cells decreased the development of collagen-induced arthritis and might help to explain the sex differences observed in human inflammatory arthritis.

Keyphrases

induced apoptosis
rheumatoid arthritis
high glucose
cell cycle arrest
endothelial cells
diabetic rats
oxidative stress
drug induced
signaling pathway
type diabetes
skeletal muscle
tissue engineering
stress induced
wild type