Association of polymorphism of IL-17A, IL-17F, and IL-6 with Toxoplasma gondii infection susceptibility in HIV/AIDS patients in Shiraz, southern Iran.

Maryam Nejabat Mohammad Reza Heydari Mohammad MotamedifarZohre ForoozanfarSaeid Amirizadeh FardAva HashempourNazani NazariEsmaeil RezaeiZahra Heydari

Published in: Immunity, inflammation and disease (2024)

The findings of this study revealed that there were significant differences in the serum levels of IL-6 and IL-17A, but not IL-17F, between the case and control groups in various genetic models. However, these polymorphisms did not show a significant relationship with toxoplasma infection in HIV-positive patients. This study represents the first investigation in Iran to explore the role of IL-6 and IL-17 polymorphisms in toxoplasma infection among HIV-positive patients.

Keyphrases

hiv positive
end stage renal disease
hiv aids
chronic kidney disease
newly diagnosed
antiretroviral therapy
ejection fraction
peritoneal dialysis
prognostic factors
toxoplasma gondii
patient reported outcomes
single cell
hiv infected