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Viral load of SARS-CoV-2 Omicron BA.5 is lower than that of BA.2 despite the higher infectivity of BA.5.

Yuna TakatsukiYuta TakahashiJun NakajimaYumi IwasakiKatsutoshi NaganoChihiro Tani-SassaSonoka YuasaSaki KanehiraKazunari SonobeYoko NukuiHiroaki TakeuchiKousuke TanimotoYukie TanakaAkinori KimuraNaoya IchimuraShuji Tohda
Published in: Immunity, inflammation and disease (2023)
The results presented here suggest that the increased infectivity of BA.5 is not caused by higher viral loads, but presumably by other factors such as increased affinity to human cell receptors or immune escape due to its L452R mutation.
Keyphrases
  • sars cov
  • endothelial cells
  • single cell
  • respiratory syndrome coronavirus
  • cell therapy
  • mesenchymal stem cells
  • mass spectrometry
  • bone marrow