High discontinuation rate of azathioprine in autoimmune hepatitis, independent of time of treatment initiation.

Simon PapeTom J G GeversJan Maarten VrolijkBart van HoekGerd BoumaCarin M J van NieuwkerkRichard TaubertElmar JaeckelMichael P MannsMaria PappNora SipekiFelix StickelCumali EfeErsan OzaslanTugrul PurnakFrederik NevensDominik J N KessenerAlisan KahramanHeiner WedemeyerJohannes HartlChristoph SchrammAnsgar Wilhelm LohseMichael A HeneghanJoost Paulus Hubertus Drenth

Published in: Liver international : official journal of the International Association for the Study of the Liver (2020)

The discontinuation rate of AZA in AIH treatment is ~15% in the first year of treatment. Early or delayed AZA initiation does not differ in remission and discontinuation rates in AIH induction therapy. Our data suggest that either strategy may be used as part of AIH treatment.

Keyphrases

stem cells
machine learning
mesenchymal stem cells
deep learning
bone marrow
data analysis
ulcerative colitis