Liver function test abnormalities in a longitudinal cohort of Thai individuals treated since acute HIV infection.
Michael J PelusoDonn J ColbySuteeraporn PinyakornSasiwimol UbolyamJintana IntasanRapee TrichavarojNitiya ChomcheyPeeriya PrueksakaewBonnie M SlikeShelly J KrebsNingbo JianMerlin L RobbPraphan PhanuphakPraphan PhanuphakSerena SpudichJintanat AnanworanichEugène Kroonnull nullPublished in: Journal of the International AIDS Society (2020)
One in six people with acute HIV infection have elevated LFTs. Clinical outcomes with ART started in acute HIV are generally good, with resolution of ALT elevations within 48 weeks on ART in most cases. These results suggest a multifactorial model for hepatic injury involving a combination of HIV-associated and ART-associated processes, which may change over time.