The Importance of Suppressing Pathological Periostin Splicing Variants with Exon 17 in Both Stroma and Cancer.

Kana ShibataNobutaka KoibuchiFumihiro SanadaNaruto KatsuragiYuko KanemotoYasuo TsunetoshiShoji IkebeKoichi YamamotoRyuichi MorishitaKenzo ShimazuYoshiaki Taniyama

Published in: Cells (2024)

These findings suggest that it is important to suppress POSTN exon 17 in both stroma and cancer. Antibody targeting POSTN exon 17 may be a therapeutic candidate for breast cancer.

Keyphrases

papillary thyroid
squamous cell
childhood cancer
signaling pathway
lymph node metastasis
gene expression
young adults
dna methylation