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The evolution and mutational robustness of chromatin accessibility in Drosophila.

Samuel KhodurskyEric B ZhengNicolas SvetecSylvia M DurkinSigi BenjaminAlice GadauXia WuLi Zhao
Published in: Genome biology (2023)
These results demonstrate the conservation of the sequence determinants of accessibility and the general robustness of chromatin accessibility, as well as the power of deep neural networks to explore fundamental questions in regulatory genomics and evolution.
Keyphrases
  • neural network
  • transcription factor
  • dna damage
  • gene expression
  • genome wide
  • single cell
  • dna methylation