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Signet ring cell variant of follicular thyroid carcinoma: Report of two cases with focus on morphological, expressional and genetic characteristics.

Martin HysekKenbugul JattaAdam StenmanEva Darai-RamqvistJan ZedeniusAnders HöögCarl Christofer Juhlin
Published in: Diagnostic pathology (2019)
The SRC-FTCs described herein were small, TERT promoter wildtype tumors exhibiting low proliferation, thereby suggesting that these exceedingly rare lesions probably carry a favorable prognosis - although the scarce availability regarding descriptions of this tumor entity nevertheless might justify careful clinical monitoring and mandate investigations in larger case series.
Keyphrases
  • dna methylation
  • single cell
  • tyrosine kinase
  • cell therapy
  • signaling pathway
  • gene expression
  • genome wide
  • transcription factor
  • copy number