Carrier-Free CXCR4-Targeted Nanoplexes Designed for Polarizing Macrophages to Suppress Tumor Growth.

Michael B DeciMaixian LiuJacqueline GonyaChristine J LeeTingyi LiScott W FergusonEmily E BonacquistiJinli WangJuliane Nguyen

Published in: Cellular and molecular bioengineering (2019)

We engineered a novel class of non-toxic RNA-protein nanoplexes that modulate the tumor stroma. These nanoplexes are promising candidates for add-ons to clinically approved chemotherapeutics.

Keyphrases

cancer therapy
protein protein
amino acid
binding protein
drug administration
nucleic acid