Target-controlled infusion of dexmedetomidine effect-site concentration for sedation in patients undergoing spinal anaesthesia.

Kyung Mi KimKwon Hui SeoJung Min LeeEun Young ParkJieun Park

Published in: Journal of clinical pharmacy and therapeutics (2019)

We applied effect-site TCI of dexmedetomidine in patients undergoing spinal anaesthesia for the first time. Dexmedetomidine Ce correlated significantly with MOAA/S scale and BIS, and was 0.89 and 1.19 ng/mL for moderate and deep sedation, respectively.

Keyphrases

patients undergoing
cardiac surgery
spinal cord
mechanical ventilation
low dose
high intensity
acute kidney injury