Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study.

Ning DingXin WangMarc G WeisskopfDavid SparrowJoel SchwartzHoward HuSung Kyun Park

Published in: PloS one (2016)

Our findings suggest that lead-related loci as a whole may play an important role in susceptibility to lead-related CHD risk. These findings need to be validated in a separate cohort containing bone lead, lead-related genetic loci and incident CHD data.

Keyphrases

genome wide
cardiovascular disease
dna methylation
genome wide association study
copy number
machine learning
electronic health record
body composition
deep learning
bone regeneration