Small intestinal metabolomics analysis reveals differentially regulated metabolite profiles in obese rats and with prebiotic supplementation.

Rachel K MeyerMegan A BimeFrank A Duca

Published in: Metabolomics : Official journal of the Metabolomic Society (2022)

Obesity is associated with a distinct small intestinal metabolome, and OFS supplementation reverses some metabolite levels that were altered in obese rats. Future research into the effects of specific metabolites identified in this study will provide deeper insight into the mechanism of fiber supplementation on improved body weight.

Keyphrases

body weight
weight loss
metabolic syndrome
type diabetes
adipose tissue
insulin resistance
bariatric surgery
mass spectrometry
ms ms
obese patients
transcription factor
weight gain
physical activity
body mass index