Clioquinol and 8-hydroxyquinoline-5-sulfonamide derivatives damage the cell wall of Pythium insidiosum.

Bruna PippiRégis A ZanetteAngélica R JoaquimMaria E KrummenauerSimone MerkelPaula ReginattoMarilene H VainsteinSaulo Fernandes de AndradeAlexandre M FuentefriaJuliana S M TondoloÉrico S LoretoJanio M Santurio

Published in: Journal of applied microbiology (2022)

Together, these results reinforce the potential of 8-HQs for developing new drugs to treat pythiosis.

Keyphrases

cell wall
oxidative stress
human health
structure activity relationship
drug induced