Chronic alcoholism associated with diabetes induced apoptosis in the corpus cavernosum of rats.
Bruno César SchimmingMucio Luiz de Assis CirinoFermino Sanches Lizarte NetoPaulo Cezar NovaisCamila Albuquerque Melo de CarvalhoDaniela Pretti da Cunha TirapelliCarlos Augusto Fernandes MolinaLuís Fernando TirapelliSilvio Tucci JuniorPublished in: Acta cirurgica brasileira (2020)
The association of these factors (ethanol and diabetes) probably can affect the apoptosis mechanism in lesions of the cavernous tissue in the rat penis. Both gene and protein expression of Caspase-9 in diabetic and ethanol-diabetic groups suggest the involvement of the apoptosis cascade from this study model.