Comparison of the ratio of second trimester fetal biometric measurements to fetal nasal bone length in fetuses with normal karyotype and trisomy 21.

Yusuf Dal Fatih Akkus Şebnem Karagün Ayhan Coşkun

Published in: Journal of clinical ultrasound : JCU (2024)

We found that BPD/NBL, HC/NBL, FL/NBL, and HL/NBL ratios differed between fetuses with a normal karyotype and those with trisomy 21, specifically the HC/NBL ratio, which predicted trisomy 21 with good diagnostic accuracy. In identifying normal-karyotype fetuses, the NBL MoM was highly accurate.

Keyphrases

gestational age
preterm birth
bone mineral density
high resolution
mass spectrometry
pregnancy outcomes